Claritin is an antihistamine that take a bit longer to build up in your system as opposed to the older antihistamines like Benadryl. The plus side is there is minimal drowsiness. What cold medicines can I take while on Zoloft?. Thus, they have little anticholinergic effect. These include Claritin, Allegra, and Zyrtec. Of these, only Zyrtec has much of an anticholinergic (i.e. drying) effect. Their main use is to block antihistamine from its receptor and reduce allergic symptoms. If your allergies cause you to have intolerably watery eyes, then the best option is. It's better not to take Benadryl (diphenhydramine) on a regular basis. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Kinlan on zoloft and claritin: Do you need both chlortrimeton and benadryl (diphenhydramine)? Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Kinlan on zoloft and claritin interaction: Alcohol is a central nervous depressant while wellbutrin (bupropion) and vyvanse are psycho-stimulants. You could end up highly intoxicated and poorly coordinated lead to falls while at the same time agitated and even psychotic. Claritin and Zoloft interaction | Treato Can I take Claritin with Zoloft? There is no known interaction between Claritin and Zoloft in our records. However, an interaction may still exist. I take zyrtec or allegra with my zoloft and I just take it the opposite of when I take the zoloft. Like I take my allergy meds at night and zoloft in am. I'm not sure if it matters, but that's how I do it. Can I take Claritin with Zoloft? There is no known interaction between Claritin and Zoloft in our records. However, an interaction may still exist. There is no known interaction between Claritin and Zoloft in our records. Summary. Drug interactions are reported among people who take Zoloft and Claritin together. This study is created by eHealthMe based on reports of 1,544 people who take Zoloft and Claritin from FDA, and is updated regularly. Can I take Claritin plain with xanax and Zoloft - Answered by a verified Doctor We use cookies to give you the best possible experience on our website. By continuing to use this site you consent to the use of cookies on your device as described in our cookie policy unless you have disabled them. i dont think you can but im only in 7th grade but i heard it on t.v. when i was watching that commercial.